Possible involvement of corticosterone and serotonin in antidepressant and antianxiety effects of chromium picolinate in chronic unpredictable mild stress induced depression and anxiety in rats. Dubey VK, Ansari F, Vohora D, Khanam R.Effectiveness of chromium in atypical depression: a placebo-controlled trial.

Davidson JR, Abraham K, Connor KM, McLeod MN.Possible adverse effects to a high dose of Chromium intake include:Īll mineral supplements should be consumed with caution in the following conditions: The usual symptoms of discomfort after Chromium supplementation include:

Since Chromium affects sleep cycles, it is better to take the supplements in the morning. Take the prescribed dosage of powder and mix it with a liquid. People who do not want tablets or capsules can buy the powder form. These supplements are available in the form of tablets and capsules that are swallowed with water. People with documented Chromium deficiency should always consult their physician before consuming any supplements. Foods rich in Chromium are vegetables (potato, broccoli), fruits, whole-grain condiments, beef, poultry, and dairy products. Mineral deficiencies can be avoided with a good diet. Both of these mechanisms bring about an improvement in depression. CrP also downregulates the levels of stress hormone (corticosterone) in the plasma. Increased insulin sensitivity upregulates the concentration of serotonin in the brain. This causes peripheral insulin sensitivity. Serotonergic activity in the brain is affected by changes in peripheral insulin.Ĭhromium Picolinate (CrP) is implicated in the treatment of depression as it increases the number of insulin receptors. A feature distinctive to depression in terms of metabolism is insulin resistance. Fluctuations in the monoamine (serotonin, dopamine) transmission system leads to depression and other mood-related mental disorders. In addition to glucose metabolism, Chromium is linked to reducing the symptoms of atypical depression. Tyrosine Kinase is an insulin receptor that gets activated by the action of Chromium. Brand Names: GTF Chromium, Chromium SynergyĪvailable Dosage forms: Oral tablets, capsules, powder, injection Courtesy: Unsplash What is Chromium?Ĭhromium is a trace mineral that is involved in the metabolism of glucose, cholesterol, and insulin.

Chromium side effects